Tyrael prefers to retain his mortal form . However, he returns to his angelic family to become both an Aspect of Justice and of Wisdom. Diablo 3 ends with him looking to see if his new mortal companion, who could be corrupted, will soon become the next threat to buy Diablo IV Gold Heaven, Hell, and Sanctuary or even life itself. In the end, The Aspect of Justice and Wisdom probably won't stand by as Inarius takes on an army of Hell to find his former love, Lilith.

The most recent Diablo 4 cinematic trailer from Blizzard is a scene of Inarius in a battle against Lilith as well as armies on both of their backs. While the scene does not mention Tyrael's personal involvement, his development of Horadrim as well as his influence on the various Paladins of Sanctuary indicates that he's in the game. Dark and light battle on the battlefield and the now-dead Tyrael is somewhere between.

His presence will be detected through these intermediaries, unless events make him a victim. Tyrael is still feeling the effects of destroying his Worldstone at the end of Diablo 2. That mystical artifact protected Sanctuary from Heaven and Hell, and he now stands as protector over the land on its behalf. Tyrael doesn't appear to be leading any further expeditions into Hell or travel any further that his current position at the Pandemonium Fortress Diablo 4 Gold, where he may provide guidance like Deckard Cain for those who are willing to listen.